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Dr. Yoshifumi Saisho

 Keio University School of Medicine, Japan


Volume 3 Issue 1

Volume 2 Issue 1

Volume 1 Issue 1

           type 2 diabetes

Therapy for Type 2 Diabetes Mellitus: Targeting the ‘Unlucky Thirteen’

Glycemic control in diabetes mellitus is a key strategy to prolong survival and mitigate complications of diabetes. Understanding the pathophysiological mechanisms contributing to diabetes has resulted in newer targets and is clinically useful for personalized management plans.


              Carotid Intima Media Thickness Test CIMT 765x2221

The Progression of Carotid Intima-Media Thickness in Subjects of Type 2 Diabetes with an Increased Urine Albumin Excretion - A Two Years Follow-up Study Increased Urine Albumin Excretion - A Two Years  Follow-up Study

Type 2 diabetes mellitus (DM) is characterized by early development of atherosclerosis resulting in high mortality and morbidity. Moreover, in patients with type 2 DM, the presence of nephropathy is associated with poor renal and cardiovascular outcome. Albuminuria is a characteristic aspect of diabetic nephropathy, while it is also a marker for increased risk of cardiovascular disease (CVD) associated with endothelial dysfunction.


MCPIP1 Deficiency Increases Insulin Sensitivity But Impairs Hepatic Insulin Signal Transduction in Mice

Chronic inflammation is associated with pathogenesis of metabolic disorders, including insulin resistance. MCPIP1 (monocyte chemotactic protein [MCP]–induced protein 1; also known as ZC3H12A) is a newly discovered RNase that is essential in controlling inflammatory response and immune homeostasis.

Journal Highlights

  • Hormone Metabolism
  •  Hormonal Receptors
  •  Signaling Mechanisms
  •  Pediatric Endocrinology
  •  Endocrine Pharmacology
  •  Molecular Endocrinology
  •  Coronary Heart Disease
  •  Diabetic Complications
  •  Diabetic Nephropathy
  •  Diabetic Neuropathy
  •  Diabetic Retinopathy
  •  Gastrointestinal Disorders
  •  Gestational Diabetes
  •  Glomerular Filtration Rate
  •  Glucose Tolerance Test
  •  Islet Transplantation
  •  Islets of Langerhans
  •  Type 1 Diabetes
  •  Type 2 Diabetes
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